The CDF experiment at the Fermilab Tevatron has been significantly upgraded for the collider Run II, which started in March 2001 and is scheduled to last until 2006. Instantaneous luminosities of 1032 cm-2 s-1 and above are expected. A data acquisition system capable of efficiently recording the data has been one of the most critical elements of the upgrade. Key figures are the ability to deal with the short bunch spacing of 132 ns, event sizes of the order of 250 kB, and permanent logging of 20 MB/s. The design of the system and experience from the first months of data-taking operation are discussed.