Using the data samples collected with the CDF Run II detector during 2002 and early 2003, new measurements of the production cross sections of charm and beauty hadrons at sqrt s = 1960 GeV are presented. New measurements of the cross sections of centrally produced b-hadrons and J/psi mesons down to zero transverse momenta have been carried out. The large charm signals made available by the silicon vertex track trigger have enabled the measurement of the cross sections of D^0, D^*, D^+/-, and D_s mesons.