The presence of extra dimensions can be probed in high energy collisions via the production or exchange of gravitons. The former corresponds to signatures with missing energy while the latter corresponds to modifications of the final state spectra. Here I review results of analyses performed by the CDF and D0 Collaborations on p anti-p collisions at s**(1/2) = 1.96 TeV in signatures sensitive to large extra dimensions. These include analyses of gamma + missing E(t) and jet + missing E(t) as signatures of graviton production as well as analyses of dilepton and diboson final states sensitive to graviton exchange.